<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Faslodex</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#code> "C1379"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P97> "<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>A synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen available to tumor cells), fulvestrant binds competitively to estrogen receptors in breast cancer cells, resulting in estrogen receptor deformation and decreased estrogen binding. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P322> "FDA"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://www.w3.org/2000/01/rdf-schema#label> "Fulvestrant"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://linked.opendata.cz/ontology/mesh/hasConcept> <http://linked.opendata.cz/resource/mesh/concept/M0397101> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>fulvestrant</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000306498</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>ZD9238</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P325> "<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>A drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the treatment of other types of cancer. Faslodex blocks estrogen activity in the body and is a type of antiestrogen.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P175> "719276"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Fulvestrant</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>DCP</n0:term-source><n0:source-code>20048</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P302> "Hormone receptor-positive metastatic breast cancer"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>FULVESTRANT</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>22X328QOC4</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P368> "CHEBI:31638"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106> "Pharmacologic Substance"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P319> "22X328QOC4"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P207> "C0935916"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Class> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://www.w3.org/2002/07/owl#sameAs> <http://linked.opendata.cz/resource/fda-spl/ingredient/22X328QOC4> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://www.w3.org/2002/07/owl#sameAs> <http://linked.opendata.cz/resource/ndfrt/ingredient/N0000010122> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#A8> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>7a-[9-[(4,4,5,5,5,-Pentafluoropentyl)sulphinyl]nonyl]-estra-1,3,5(10)-triene-3,17b-diol</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://www.w3.org/2000/01/rdf-schema#subClassOf> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1821> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Faslodex</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000415316</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P210> "129453-61-8"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P303> "Breast cancer; Endometrial cancer; Prostate cancer"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P366> "Fulvestrant"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106> "Organic Chemical"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Faslodex(ICI 182,780)</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0719276</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P330> "43053"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P329> "43053"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P350> "C32H47F5O3S"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Fulvestrant</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P108> "Fulvestrant"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>ICI 182780</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000045005</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1379> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>ICI 182,780</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .