"leuprolide acetatePTNCI-GLOSSCDR0000595341" . "74381-53-6"^^ . "C0700596"^^ . "Lupron Depot-PedBRNCI" . . . "ProstapFBNCI" . "GinecrinFBNCI" . "CarcinilFBNCI" . "6-D-Leucine-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (Pig) MonoacetateSNNCI" . "ProcrenFBNCI" . "Pharmacologic Substance"^^ . "40058"^^ . . "ViadurPTNCI-GLOSSCDR0000595349" . "Abbott 43818CNNCI" . "TrenantoneFBNCI" . "377526"^^ . _:vb686831 . "C1319"^^ . "LEUPABNCI" . "40058"^^ . "A-43818CNNCI" . "37JNS02E7V"^^ . . . "Lupron Depot-4 MonthBRNCI" . _:vb686832 . "Abbott-43818CNNCI" . "A drug used to treat symptoms of advanced prostate cancer. It is also being studied in the treatment of other conditions and types of cancer. The active ingredient leuprolide blocks the body from making testosterone (a male hormone) and estradiol (a female hormone). It may stop the growth of prostate cancer cells that need testosterone to grow. Some brands of leuprolide are also used to treat early puberty in children and certain gynecologic conditions. Leuprolide acetate is a type of gonadotropin-releasing hormone analog.NCI-GLOSS" . "6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) MonoacetateSNNCI" . _:vb686832 . _:vb686832 . "ViadurBRNCI" . "LupronPTNCI-GLOSSCDR0000595348" . "FDA"^^ . _:vb686831 . "EnantonFBNCI" . "CHEBI:63597"^^ . "The acetate salt of a synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression.NCI" . _:vb686829 . "Leuprolide Acetate"^^ . _:vb686830 . "Alzheimer disease; Prostate cancer"^^ . "Leuprolide AcetatePTNCI" . _:vb686831 . "LucrinFBNCI" . "Leuprorelin AcetateSYNCI" . _:vb686830 . "TAP-144CNNCI" . "LupronBRNCI" . "LEUPROLIDE ACETATEPTFDA37JNS02E7V" . . _:vb686831 . "Uno-EnantoneFBNCI" . . _:vb686829 . "Lupron Depot-3 MonthBRNCI" . "Endometriosis; In-vitro fertilization; Precocious puberty; Premenstrual syndrome; Prostate cancer; Uterine fibroid tumors"^^ . "Amino Acid, Peptide, or Protein"^^ . "Lupron DepotBRNCI" . _:vb686829 . _:vb686829 . "EligardPTNCI-GLOSSCDR0000595347" . "EnantoneFBNCI" . "Depo-EligardFBNCI" . _:vb686830 . "LeuplinFBNCI" . "Leuprolide"^^ . _:vb686832 . _:vb686830 . "Leuprolide AcetatePTDCP31429" . "Enantone-GynFBNCI" . "Leuprolide Acetate"^^ . "Lucrin DepotFBNCI" . "C59H84N16O12.C2H4O2"^^ . "ProcrinFBNCI" .