<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>DCP</n0:term-source><n0:source-code>01195</n0:source-code></n0:ComplexTerm>" .
_:vb718858	<http://www.w3.org/2002/07/owl#someValuesFrom>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17573> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P366>	"Tacrolimus"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P319>	"WM0HAQ4WNM"^^<http://www.w3.org/2001/XMLSchema#string> .
_:vb718860	<http://www.w3.org/2002/07/owl#onProperty>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R122> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#subClassOf>	_:vb718858 .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#subClassOf>	_:vb718859 .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#subClassOf>	_:vb718860 .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P207>	"C0085149"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>FK 506</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P108>	"Tacrolimus"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2002/07/owl#sameAs>	<http://linked.opendata.cz/resource/ndfrt/ingredient/N0000007302> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Fujimycin</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P175>	"717865"^^<http://www.w3.org/2001/XMLSchema#string> .
_:vb718860	<http://www.w3.org/2002/07/owl#someValuesFrom>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C46000> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#subClassOf>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C574> .
_:vb718859	<http://www.w3.org/2002/07/owl#someValuesFrom>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45999> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P330>	"42009"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P302>	"Atopic dermatitis; Kidney transplant rejection, prophylaxis; Liver transplant rejection, prophylaxis"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Protopic</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://linked.opendata.cz/ontology/mesh/hasConcept>	<http://linked.opendata.cz/resource/mesh/concept/M0025261> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#code>	"C1311"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P97>	"<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>A macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P350>	"C44H69NO12.H2O"^^<http://www.w3.org/2001/XMLSchema#string> .
_:vb718859	<http://www.w3.org/2002/07/owl#onProperty>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R122> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>tacrolimus</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000045414</n0:source-code></n0:ComplexTerm>" .
_:vb718858	<http://www.w3.org/2002/07/owl#onProperty>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R122> .
_:vb718858	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.w3.org/2002/07/owl#Restriction> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.w3.org/2002/07/owl#Class> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106>	"Antibiotic"^^<http://www.w3.org/2001/XMLSchema#string> .
_:vb718859	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.w3.org/2002/07/owl#Restriction> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#A8>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#label>	"Tacrolimus"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P322>	"FDA"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P368>	"CHEBI:61057"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Tacrolimus</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>TACROLIMUS</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>WM0HAQ4WNM</n0:source-code></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P303>	"Graft versus Host Disease, prevention; Kidney transplantation rejection, prevention"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Prograf</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P329>	"42009"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2002/07/owl#sameAs>	<http://linked.opendata.cz/resource/fda-spl/ingredient/WM0HAQ4WNM> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P325>	"<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>A drug used to help reduce the risk of rejection by the body of organ and bone marrow transplants.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90>	"<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Tacrolimus</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0717865</n0:source-code></n0:ComplexTerm>" .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106>	"Organic Chemical"^^<http://www.w3.org/2001/XMLSchema#string> .
_:vb718860	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.w3.org/2002/07/owl#Restriction> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://www.w3.org/2000/01/rdf-schema#subClassOf>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2201> .
<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1311>	<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P210>	"109581-93-3"^^<http://www.w3.org/2001/XMLSchema#string> .