This HTML5 document contains 30 embedded RDF statements represented using HTML+Microdata notation.

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Namespace Prefixes

Prefix	IRI
n8	http://linked.opendata.cz/resource/mesh/concept/
rdfs	http://www.w3.org/2000/01/rdf-schema#
n6	http://linked.opendata.cz/resource/fda-spl/ingredient/
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#
n7	http://linked.opendata.cz/ontology/mesh/
owl	http://www.w3.org/2002/07/owl#
nci	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
n5	http://linked.opendata.cz/resource/ndfrt/ingredient/
xsdh	http://www.w3.org/2001/XMLSchema#

Statements

Subject Item

nci:C499

rdf:type

owl:Class

rdfs:label

Flecainide Acetate

rdfs:subClassOf

nci:C93038 nci:C47793 _:vb673678

nci:A6

nci:C62029

nci:A8

nci:C63923

nci:P106

Pharmacologic Substance Organic Chemical

nci:P108

Flecainide Acetate

nci:P175

719273

nci:P207

C0086303

nci:P210

54143-56-5

nci:P319

M8U465Q1WQ

nci:P322

FDA

nci:P329

41626

nci:P330

41626

nci:P350

C17H20F6N2O3.C2H4O2

nci:P366

Flecainide

nci:P90

<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>FLECAINIDE ACETATE</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>M8U465Q1WQ</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Flecainide Acetate</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>

nci:P97

<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>The acetate salt form of flecainide, a synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>

nci:P98

Flecainide is used to prevent paroxysmal supraventricular tachycardias, atrial fibrillations and flutter, and other arrhythmias. It also relieves neuropathic pain from damage to nerves caused by some cancers.

nci:code

C499

owl:sameAs

n5:N0000179311 n6:M8U465Q1WQ

n7:hasConcept

n8:M0330385

Subject Item

_:vb673678

rdf:type

owl:Restriction

owl:onProperty

nci:R122

owl:someValuesFrom

nci:C17287