<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A substance that blocks signals passed from one molecule to another inside a cell. Blocking these signals can affect many functions of the cell, including cell division and cell death, and may kill cancer cells. Certain signal transduction inhibitors are being studied in the treatment of cancer.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A substance that inhibits kinase enzymes and other proteins involved in signal transduction pathways to prevent tumor cell growth and induce apoptosis.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>