This HTML5 document contains 19 embedded RDF statements represented using HTML+Microdata notation.

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Namespace Prefixes

PrefixIRI
n5http://linked.opendata.cz/resource/mesh/concept/
rdfshttp://www.w3.org/2000/01/rdf-schema#
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n4http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
ncihttp://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
nci:C1613
rdf:type
owl:Class
rdfs:label
Antineoplaston AS2-1
rdfs:subClassOf
nci:C2500
nci:P106
Pharmacologic Substance Amino Acid, Peptide, or Protein
nci:P108
Antineoplaston AS2-1
nci:P175
620261
nci:P207
C0294295
nci:P210
104624-98-8
nci:P303
Adrenal gland cancer; astrocytoma; brain tumor; breast cancer; colon cancer; ependymoma; esophageal cancer; glioblastoma multiforme; lung cancer; lymphoma; melanoma Mesothelioma; multiple myeloma; neuroectodermal tumor; pancreatic cancer; prostate cancer; rhabdoid tumor of the CNS
nci:P329
41985
nci:P330
41985
nci:P366
Antineoplaston_AS2-1
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Antineoplaston AS2-1</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0620261</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Antineoplaston AS2-1</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A 4:1 mixture of phenylacetate and phenylacetylgluatmine, degradation products of the antineoplaston agent A10. Antineoplaston AS2-1 inhibits the incorporation of L-glutamine into tumor-cell proteins, leading to cell cycle arrest in the G1 phase and inhibition of mitosis. This agent may also inhibit RAS oncogene expression and activate tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C1613
n4:hasConcept
n5:M0243025