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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Anaxirone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Anaxirone
NSC_Code
  • 332488
UMLS_CUI
  • C0043767
CAS_Registry
  • 77658-97-0
In_Clinical_Trial_For
  • Advanced Ovarian Carcinoma; Advanced Non-Small Cell Lung Cancer and Metastatic Colorectal Cancer.
FDA_UNII_Code
  • 36R61Y789T
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39194
PDQ_Closed_Trial_Search_ID
  • 39194
Chemical_Formula
  • C11H15N3O5
Legacy_Concept_Name
  • Anaxirone
FULL_SYN
  • 1,2,4-triglycidylurazolSNNCI
  • TGUABNCI
  • ANAXIRONEPTFDA36R61Y789T
  • TriglycidylurazolSYNCI
  • AnaxironePTNCI
DEFINITION
  • A synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been shown to exhibit a broad spectrum of antineoplastic activity against experimental tumors, including those resistant to other alkylating agents.NCI
code
  • C950
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