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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Trebananib
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Trebananib
UMLS_CUI
  • C1541521
CAS_Registry
  • 894356-79-7
FDA_UNII_Code
  • X8Y5U6NC7E
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 423474
PDQ_Closed_Trial_Search_ID
  • 423474
FULL_SYN
  • Angiopoietin 1/2-Neutralizing Peptibody AMG 386SYNCI
  • AMG 386CNNCI
  • TREBANANIBPTFDAX8Y5U6NC7E
  • TrebananibPTNCI
DEFINITION
  • An angiopoietin (Ang) 1 and 2 neutralizing peptibody, with potential antiangiogenic activity. AMG 386 targets and binds to Ang1 and Ang2, thereby preventing the interaction of the angiopoietins with their target tie2 receptors. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.NCI
code
  • C91711
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