About: Hedgehog Inhibitor PF-04449913     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hedgehog Inhibitor PF-04449913
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hedgehog Inhibitor PF-04449913
NCI_META_CUI
  • CL412426
PDQ_Open_Trial_Search_ID
  • 652940
PDQ_Closed_Trial_Search_ID
  • 652940
FULL_SYN
  • Hedgehog Inhibitor PF-04449913PTNCI
DEFINITION
  • An orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF-04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies.NCI
code
  • C84862
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