About: Ambenonium Chloride Tetrahydrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ambenonium Chloride Tetrahydrate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ambenonium Chloride Tetrahydrate
UMLS_CUI
  • C2698080
CAS_Registry
  • 52022-31-8
FDA_UNII_Code
  • 9T1OT01KW1
Contributing_Source
  • FDA
Chemical_Formula
  • C28H42Cl2N4O2.2Cl.4H2O
Legacy_Concept_Name
  • Ambenonium_Chloride_Tetrahydrate
FULL_SYN
  • Ambenonium Chloride TetrahydratePTNCI
  • AMBENONIUM CHLORIDE TETRAHYDRATEPTFDA9T1OT01KW1
DEFINITION
  • The tetrahydrate and chloride salt form of ambenonium, a bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding to the anionic site at the reactive center of acetylcholinesterase, preventing the breakdown of acetylcholine and producing an indirect cholinomimetic effect at both nicotinic and muscarinic receptors. Ambenonium also has direct agonist activity at nicotinic receptors, potentiating the cholinomimetic effect at the neuromuscular junction.NCI
code
  • C79523
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