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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Puromycin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Puromycin
NSC_Code
  • 3055
UMLS_CUI
  • C0034145
CAS_Registry
  • 53-79-2
FDA_UNII_Code
  • 4A6ZS6Q2CL
Contributing_Source
  • FDA
ALT_DEFINITION
  • An antibiotic from Streptomyces alboniger that inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.MSH2002_06_01
Chemical_Formula
  • C22H29N7O5
Legacy_Concept_Name
  • Puromycin
CHEBI_ID
  • CHEBI:17939
FULL_SYN
  • PuromycineSYNCI
  • StylomycinSYNCI
  • StillomycinSYNCI
  • PuromycinumSYNCI
  • PuromycinPTDCP07447
  • Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, L-SNNCI
  • Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-SNNCI
  • P-638CNNCI
  • L-3'-(alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosineSNNCI
  • PUROMYCINPTFDA4A6ZS6Q2CL
  • CL 16536CNNCI
  • PuromycinSYDTPNSC0003055
  • PuromycinPTNCI
  • PuromicinaSYNCI
DEFINITION
  • An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture. (NCI04)NCI
code
  • C787
sameAs
http://linked.open...y/mesh/hasConcept
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