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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ambenonium
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ambenonium
UMLS_CUI
  • C0002412
CAS_Registry
  • 7648-98-8
FDA_UNII_Code
  • L16PUN799N
Contributing_Source
  • FDA
Chemical_Formula
  • C28H42Cl2N4O2
Legacy_Concept_Name
  • Ambenonium
CHEBI_ID
  • CHEBI:2627
FULL_SYN
  • Benzenemethanaminium, N,N'-((1,2-dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl))bis(2-chloro-N,N-diethyl-SNNCI
  • AMBENONIUMPTFDAL16PUN799N
  • AmbenoniumPTNCI
DEFINITION
  • A bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding to the anionic site at the reactive center of acetylcholinesterase, preventing the breakdown of acetylcholine and producing an indirect cholinomimetic effect at both nicotinic and muscarinic receptors. Ambenonium also has direct agonist activity at nicotinic receptors, potentiating the cholinomimetic effect at the neuromuscular junction.NCI
code
  • C76136
is Has_Free_Acid_Or_Base_Form of
is sameAs of
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