About: Puromycin Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Puromycin Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Puromycin Hydrochloride
UMLS_CUI
  • C0282329
CAS_Registry
  • 58-58-2
FDA_UNII_Code
  • PGN54228S5
Contributing_Source
  • FDA
Chemical_Formula
  • C22H29N7O5.2HCl
Legacy_Concept_Name
  • Puromycin_Hydrochloride
FULL_SYN
  • Puromycin HydrochloridePTNCI
  • PUROMYCIN HYDROCHLORIDEPTFDAPGN54228S5
DEFINITION
  • The hydrochloride salt form of puromycin, an aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture.NCI
code
  • C75148
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
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