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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pirbenicillin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pirbenicillin
UMLS_CUI
  • C0071128
CAS_Registry
  • 55975-92-3
FDA_UNII_Code
  • 8ARY01XRYU
Contributing_Source
  • FDA
Chemical_Formula
  • C24H26N6O5S
Legacy_Concept_Name
  • Pirbenicillin
FULL_SYN
  • PIRBENICILLINPTFDA8ARY01XRYU
  • PirbenicillinPTNCI
DEFINITION
  • A semisynthetic penicillin with antibacterial activity. Pirbenicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C66414
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