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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mephenytoin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Mephenytoin
NSC_Code
  • 34652
UMLS_CUI
  • C0025381
CAS_Registry
  • 50-12-4
FDA_UNII_Code
  • R420KW629U
Contributing_Source
  • FDA
Chemical_Formula
  • C12H14N2O2
Legacy_Concept_Name
  • Mephenytoin
FULL_SYN
  • 3-Methyl-5,5-phenylethylhydantoinSNNCI
  • MephenytoinPTNCI
  • 3-EthylnirvanolSYNCI
  • 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-SNNCI
  • MEPHENYTOINPTFDAR420KW629U
DEFINITION
  • A heterocyclic organic compound with anticonvulsant property. Although the mechanism of action is not well established, mephenytoin potentially promotes sodium efflux from neurons in motor cortex, and stabilizes the threshold against hyperexcitability caused by excessive stimulation. Thus this agent reduces the membrane sodium gradient and prevents cortical seizure signal spreading. It may cause blood dyscrasias, therefore, this agent was only used after other less toxic anticonvulsants had failed.NCI
code
  • C66091
sameAs
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