About: Demecarium Bromide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Demecarium Bromide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Demecarium Bromide
UMLS_CUI
  • C0057361
CAS_Registry
  • 56-94-0
FDA_UNII_Code
  • 61D5V4OKTP
Contributing_Source
  • FDA
Chemical_Formula
  • C32H52N4O4.2Br
Legacy_Concept_Name
  • Demecarium_Bromide
CHEBI_ID
  • CHEBI:4391
FULL_SYN
  • VisumioticSYNCI
  • (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis(methylcarbamate) (2:1)SNNCI
  • Demecarium BromidePTNCI
  • DEMECARIUM BROMIDEPTFDA61D5V4OKTP
  • HumorsolBRNCI
DEFINITION
  • The bromide salt form of demecarium, a quaternary ammonium compound and a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity. This causes contraction of the iris sphincter muscle (producing miosis) and the ciliary muscle (affecting the accommodation reflex). In so doing, this agent increases the outflow of the aqueous humor, thereby reducing intraocular pressure.NCI
code
  • C65367
sameAs
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