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AttributesValues
rdf:type
rdfs:label
  • Cyanocobalamin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Vitamin
Preferred_Name
  • Cyanocobalamin
NSC_Code
  • 80365
UMLS_CUI
  • C1964367
CAS_Registry
  • 68-19-9
FDA_UNII_Code
  • P6YC3EG204
Contributing_Source
  • FDA
ALT_DEFINITION
  • A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Cyanocobalamin helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Cyanocobalamin is water-soluble (can dissolve in water) and must be taken in every day. Not enough cyanocobalamin can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40295
PDQ_Closed_Trial_Search_ID
  • 40295
Chemical_Formula
  • C63H89CoN14O14P
Legacy_Concept_Name
  • Cyanocobalamin
CHEBI_ID
  • CHEBI:17439
FULL_SYN
  • Vitamin B12SYNCI
  • CYANOCOBALAMINPTFDAP6YC3EG204
  • CyanocobalaminPTNCI
  • CyanocobalaminSYDTPNSC0080365
  • cyanocobalaminPTNCI-GLOSSCDR0000580772
  • CobaviteBRNCI
  • CalomistBRNCI
  • BerubigenBRNCI
  • Betalin 12BRNCI
DEFINITION
  • A cobalt-containing coordination compound generated by intestinal microbes, and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.NCI
code
  • C64333
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