About: Mannitol     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mannitol
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Carbohydrate
  • Pharmacologic Substance
Preferred_Name
  • Mannitol
NSC_Code
  • 407017
UMLS_CUI
  • C0024730
CAS_Registry
  • 69-65-8
FDA_UNII_Code
  • 3OWL53L36A
Contributing_Source
  • FDA
ALT_DEFINITION
  • A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.MSH2002_06_01
  • A drug used to decrease swelling of the brain and to treat kidney failure. Mannitol can also be used to open the blood-brain barrier, which allows anticancer medicines to enter the brain and treat brain tumors.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39493
PDQ_Closed_Trial_Search_ID
  • 39493
Chemical_Formula
  • C6H14O6
Legacy_Concept_Name
  • Mannitol
CHEBI_ID
  • CHEBI:16899
FULL_SYN
  • Mannitol, D-SYNCI
  • D-MannitolPTDCP03076
  • MANNITOLPTFDA3OWL53L36A
  • OsmitrolSYDTPNSC0407017
  • mannitolPTNCI-GLOSSCDR0000468771
  • MannitolPTNCI
  • OsmitrolBRNCI
  • ResectisolSYDTPNSC0407017
  • D-MannitolSYNCI
  • ResectisolBRNCI
DEFINITION
  • A naturally occurring alcohol found in fruits and vegetables and used as an osmotic diuretic. Mannitol is freely filtered by the glomerulus and poorly reabsorbed from the renal tubule, thereby causing an increase in osmolarity of the glomerular filtrate. An increase in osmolarity limits tubular reabsorption of water and inhibits the renal tubular reabsorption of sodium, chloride, and other solutes, thereby promoting diuresis. In addition, mannitol elevates blood plasma osmolarity, resulting in enhanced flow of water from tissues into interstitial fluid and plasma.NCI
code
  • C625
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 44 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software