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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Halazepam
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Halazepam
UMLS_CUI
  • C0062092
CAS_Registry
  • 23092-17-3
FDA_UNII_Code
  • 320YC168LF
Contributing_Source
  • FDA
Chemical_Formula
  • C17H12ClF3N2O
Legacy_Concept_Name
  • Halazepam
FULL_SYN
  • HALAZEPAMPTFDA320YC168LF
  • PaxipamBRNCI
  • HalazepamPTNCI
DEFINITION
  • A synthetic benzodiazepine derivative with anxiolytic property. Halazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic, and hypothalamic regions of the central nervous system (CNS). This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability.NCI
code
  • C61780
sameAs
http://linked.open...y/mesh/hasConcept
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