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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cyclophosphamide Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cyclophosphamide Anhydrous
UMLS_CUI
  • C1880207
CAS_Registry
  • 50-18-0
FDA_UNII_Code
  • 6UXW23996M
Contributing_Source
  • FDA
Chemical_Formula
  • C7H15Cl2N2O2P
Legacy_Concept_Name
  • Cyclophosphamide_Anhydrous
CHEBI_ID
  • CHEBI:4027
FULL_SYN
  • N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-OxideSNNCI
  • 2H-1,3,2-oxazaphosphorin-2-amine, N,N-is(2-chloroethyl)tetrahydro-,2-oxideSNNCI
  • Cyclophosphamide AnhydrousPTNCI
  • CYCLOPHOSPHAMIDE ANHYDROUSPTFDA6UXW23996M
DEFINITION
  • The anhydrous form of cyclophosphamide, a synthetic nitrogen mustard alkylating agent, with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to active metabolites including phosphoramide mustard, which binds to and crosslinks DNA and RNA, thereby inhibiting DNA replication and protein synthesis. This agent, at low doses, is also a potent immunosuppressant primarily by depleting T-regulatory cells.NCI
code
  • C61694
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