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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • E7820
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • E7820
UMLS_CUI
  • C1172515
PDQ_Open_Trial_Search_ID
  • 363619
PDQ_Closed_Trial_Search_ID
  • 363619
Legacy_Concept_Name
  • E7820
FULL_SYN
  • E7820PTNCI
DEFINITION
  • A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.NCI
code
  • C61501
http://linked.open...y/mesh/hasConcept
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