About: F-18 Fluoroethyltyrosine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • F-18 Fluoroethyltyrosine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • F-18 Fluoroethyltyrosine
UMLS_CUI
  • C1831729
In_Clinical_Trial_For
  • Brain Tumor Imaging
PDQ_Open_Trial_Search_ID
  • 467177
PDQ_Closed_Trial_Search_ID
  • 467177
Legacy_Concept_Name
  • Fluoroethyl-L-tyrosine_F_18
FULL_SYN
  • O-2'-[F18]-Fluoroethyl-L-tyrosineSNNCI
  • Fluoroethyltyrosine F18SYNCI
  • Fluorine-18 Fluoroethyl-L-TyrosineSNNCI
  • F-18 FluoroethyltyrosinePTNCI
  • Fluorine-18 2'-Fluoroethyl-L-tyrosineSYNCI
  • Fluoroethyl-L-tyrosine F 18SNNCI
  • 18FETABNCI
  • 18F-FETABNCI
  • [18F]-Fluoro-ethyl-L-tyrosineSYNCI
  • 2'-[F18] Fluoro-ethyl-L-tyrosineSYNCI
  • O-(2[F18]fluoroethyl)-L-tyrosineSYNCI
DEFINITION
  • An amino acid analog radiolabeled with fluorine F 18, a positron emitting isotope, used as a tracer in positron emission tomography (PET). Reflecting the increased amino acid transport capacity of tumor cells, F-18 fluroethyltyrosine (F-18 FET) is actively taken up in tumor cells via the amino acid transport system, but is neither incorporated into proteins nor readily degraded, resulting in high intracellular concentrations of this imaging agent. Radiolabeled amino acid-based agents are useful in PET brain tumor imaging because F-18 fluoro-deoxyglucose (F-18 FDG), commonly used in PET tumor imaging, is relatively insensitive for detecting tumors in the brain due to high levels of glycolytic metabolism in the normal cortex and to a lesser extent in white matter.NCI
code
  • C60818
http://linked.open...y/mesh/hasConcept
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