About: Inositol 1,4,5-Trisphosphate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Inositol 1,4,5-Trisphosphate
rdfs:subClassOf
Semantic_Type
  • Lipid
  • Biologically Active Substance
Preferred_Name
  • Inositol 1,4,5-Trisphosphate
UMLS_CUI
  • C0021549
CAS_Registry
  • 85166-31-0
ALT_DEFINITION
  • Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.MSH2002_06_01
Legacy_Concept_Name
  • Inositol_1_4_5-Trisphosphate
CHEBI_ID
  • CHEBI:16595
FULL_SYN
  • IP3ABNCI
  • Inositol 1,4,5-TrisphosphatePTNCI
DEFINITION
  • A phosphatidylinositol with phosphate covalently bound in the 4 and 5 positions of the inositol group. Inositol 1,4,5-trisphosphate acts as an intermediate in the IP3/DAG pathway, hydrolyzed by phospholipase C and liberating diacylglycerol and PIP2, which activate Protein Kinase C and calcium release from the endoplasmic reticulum, respectively.NCI
code
  • C580
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 13 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software