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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Secretin Human
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Hormone
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Secretin Human
UMLS_CUI
  • C1659046
CAS_Registry
  • 108153-74-8
FDA_UNII_Code
  • A0426J905J
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to help diagnose gastrinomas (tumors that cause too much gastric acid to be made) and other problems with the pancreas. It is also used to increase secretions from the pancreas and to help identify a duct called the ampulla of Vater. Secretin human is a form of secretin that is made in the laboratory. Secretin causes the pancreas, liver, and stomach to release substances that help digest food.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 669871
PDQ_Closed_Trial_Search_ID
  • 669871
Chemical_Formula
  • C130H220N44O40
Legacy_Concept_Name
  • Secretin_Synthetic_Human
FULL_SYN
  • ChiRhoStimPTNCI-GLOSSCDR0000667147
  • synthetic human secretinPTNCI-GLOSSCDR0000667145
  • SECRETIN HUMANPTFDAA0426J905J
  • Synthetic Human SecretinSYNCI
  • Secretin HumanPTNCI
  • SHSABNCI
  • RG1068CNNCI
  • secretin humanPTNCI-GLOSSCDR0000667149
  • ChirhostimBRNCI
DEFINITION
  • A synthetic human therapeutic agent which is chemically identical or similar to endogenous secretin, a peptide hormone found in the mucosal S-cells of the proximal small intestine. Secretin stimulates the pancreatic acinar cells and ductal epithelial cells to emit bicarbonate rich digestive fluids, thereby increases duodenal bicarbonate level. Bicarbonate neutralizes acidity of the intestines, consequently increasing the pH and facilitating the action of intestinal digestive enzymes. In addition, secretin stimulates the stomach and the liver to produce pepsin and bile, respectively. Both pepsin and bile aide the digestive action of the duodenum, which resulting in the prevention of gastric inflammation.NCI
code
  • C47713
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