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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rizatriptan Benzoate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rizatriptan Benzoate
UMLS_CUI
  • C0772420
CAS_Registry
  • 145202-66-0
FDA_UNII_Code
  • WR978S7QHH
Contributing_Source
  • FDA
Chemical_Formula
  • C15H19N5.C7H6O2
Legacy_Concept_Name
  • Rizatriptan_Benzoate
FULL_SYN
  • RIZATRIPTAN BENZOATEPTFDAWR978S7QHH
  • 1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, MonobenzoateSNNCI
  • MaxaltBRNCI
  • L 705,126CNNCI
  • Rizatriptan BenzoatePTNCI
DEFINITION
  • The benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property. Rizatriptan benzoate selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Rizatriptan benzoate may also relief migraine headaches by inhibition of pro-inflammatory neuropeptide release.NCI
code
  • C47708
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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