About: Promazine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Promazine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Promazine Hydrochloride
NSC_Code
  • 17468
UMLS_CUI
  • C0546875
CAS_Registry
  • 53-60-1
FDA_UNII_Code
  • U16EOR79U4
Contributing_Source
  • FDA
Chemical_Formula
  • C17H20N2S.HCl
Legacy_Concept_Name
  • Promazine_Hydrochloride
CHEBI_ID
  • CHEBI:8460
FULL_SYN
  • Promazine HydrochloridePTNCI
  • PROMAZINE HYDROCHLORIDEPTFDAU16EOR79U4
  • 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, MonohydrochlorideSNNCI
  • TalofenSYNCI
  • SparineSYNCI
  • 10-(3-(Dimethylamino)propyl)phenothiazine MonohydrochlorideSNNCI
  • StarazinSYNCI
DEFINITION
  • The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity.NCI
code
  • C47691
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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