About: Molindone Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Molindone Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Molindone Hydrochloride
UMLS_CUI
  • C0282249
CAS_Registry
  • 15622-65-8
FDA_UNII_Code
  • 1DWS68PNE6
Contributing_Source
  • FDA
Chemical_Formula
  • C16H24N2O2.HCl
Legacy_Concept_Name
  • Molindone_Hydrochloride
FULL_SYN
  • 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, MonohydrochlorideSNNCI
  • Molindone HydrochloridePTNCI
  • MOLINDONE HYDROCHLORIDEPTFDA1DWS68PNE6
  • MobanBRNCI
  • LidoneSYNCI
DEFINITION
  • The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone hydrochloride exerts its effect by blocking dopamine receptors, probably D2 and D3, in the reticular activating and limbic systems, thereby decreasing dopamine excess in the brain. This leads to a reduction of spontaneous locomotion and aggressiveness, suppression of conditioned response, antagonism of stereotyped behaviour and hyperactivity induced by amphetamines.NCI
code
  • C47624
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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