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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ethotoin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ethotoin
UMLS_CUI
  • C0015046
CAS_Registry
  • 86-35-1
FDA_UNII_Code
  • 46QG38NC4U
Contributing_Source
  • FDA
Chemical_Formula
  • C11H12N2O2
Legacy_Concept_Name
  • Ethotoin
CHEBI_ID
  • CHEBI:4888
FULL_SYN
  • ETHOTOINPTFDA46QG38NC4U
  • Hydantoin, 3-ethyl-5-phenyl-SNNCI
  • 3-ethyl-5-phenyl-2,4-imidazolidinedioneSNNCI
  • PeganoneBRNCI
  • EthotoinPTNCI
DEFINITION
  • A hydantoin anticonvulsant with anti-epileptic activity. The mechanism of action is not completely known, but is thought to be fairly similar to phenytoin. Ethotoin influences synaptic transmission by altering sodium and calcium ion influx across neuronal membranes in the repolarization, depolarization, and membrane stability phase and interferes with the calcium uptake in presynaptic terminals. This inhibits neuronal firing and results in the stabilization of neuronal membranes, thereby preventing the spread of seizure activity at the motor cortex.NCI
code
  • C47524
sameAs
http://linked.open...y/mesh/hasConcept
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