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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Amcinonide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Amcinonide
UMLS_CUI
  • C0051556
CAS_Registry
  • 51022-69-6
FDA_UNII_Code
  • 423W026MA9
Contributing_Source
  • FDA
Chemical_Formula
  • C28H35FO7
Legacy_Concept_Name
  • Amcinonide
CHEBI_ID
  • CHEBI:31199
FULL_SYN
  • TriamcinolonacetatcyclopentanonidSYNCI
  • 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetateSNNCI
  • VisdermSYNCI
  • AMCINONIDEPTFDA423W026MA9
  • CL 34699CNNCI
  • CyclocortBRNCI
  • AmcinonidePTNCI
DEFINITION
  • A synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids. Amcinonide interacts with specific corticosteroid receptors and was internalized, which leads to binding of DNA and modification of gene expression. This results in synthesis of anti-inflammatory mediators while inhibiting synthesis of inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are achieved.NCI
code
  • C47389
sameAs
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