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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • EF5
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • EF5
NSC_Code
  • 684681
UMLS_CUI
  • C0382334
ALT_DEFINITION
  • A drug that is used to plan cancer treatment by measuring oxygen levels in tumor cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43025
PDQ_Closed_Trial_Search_ID
  • 43025
Legacy_Concept_Name
  • EF5
FULL_SYN
  • EF5SYNCI-GLOSSCDR0000045970
  • EF5PTNCI
  • EF-5SYNCI
  • 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) AcetamideSNNCI
DEFINITION
  • A fluorinated derivative of the 2-nitroimidazole etanidazole. EF5 is effective in accessing oxygen levels in tumor tissue through its adduct formation to intracellular macromolecules in the absence of oxygen. Reduction of this agent is carried out by a diverse group of enzymes in the cytoplasm, microsomes and mitochondria. Tissue hypoxia detection via EF5 has been reported in several cancers, including squamous cell carcinoma of the cervix and the head and neck, and in sarcoma.NCI
code
  • C45873
http://linked.open...y/mesh/hasConcept
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