About: Ovarian Granulosa Cell     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ovarian Granulosa Cell
rdfs:subClassOf
Semantic_Type
  • Cell
Preferred_Name
  • Ovarian Granulosa Cell
NCI_META_CUI
  • CL414869
Legacy_Concept_Name
  • Ovarian_Granulosa_Cell
FULL_SYN
  • Ovarian Granulosa CellPTNCI
DEFINITION
  • A cuboidal cell derived from a spindle-shaped granulosa cell precursor. Initially, ovarian granulosa cells create a single layer surrounding an oocyte. The oocyte and its single layer of ovarian granulosa cells make up a primary follicle. Proliferation of the ovarian granulosa cells leads to multiple cell layers surrounding the oocyte and maturation into a secondary follicle. The granulosa cells extend cytoplasmic processes to form gestational gap-junction-like unions with the plasma membrane of the oocyte. The continued growth of the ovarian granulosa cells takes the oocyte to the Graafian follicle stage. Once ovulation occurs, the granulosa cells become part of the corpus luteum. A major function of an ovarian granulosa cell is hormone production and secretion.NCI
code
  • C41607
is rdfs:subClassOf of
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