About: Tumor Necrosis Factor Signaling Process     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tumor Necrosis Factor Signaling Process
rdfs:subClassOf
Semantic_Type
  • Physiologic Function
Preferred_Name
  • Tumor Necrosis Factor Signaling Process
UMLS_CUI
  • C1519684
Legacy_Concept_Name
  • Tumor_Necrosis_Factor_Activation
FULL_SYN
  • Tumor Necrosis Factor ActivationSYNCI
  • Tumor Necrosis Factor Signaling ProcessPTNCI
DEFINITION
  • Any process which promotes expression of tumor necrosis factors, their subsequent secretion, binding to cognate receptors and intracellular signaling, and results in promoting insulin resistance, fever and macrophage phagocytosis, stimulating the hypothalmic-pituitary-adrenal axis and acute phase responses, and suppressing appetite. This process is involved in coordinating systemic responses to pathogenic infection.NCI
code
  • C40589
is someValuesFrom of
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