About: Buserelin

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Buserelin
rdfs:subClassOf	Gonadotropin-Releasing Hormone Analogue
Has_Salt_Form	Buserelin Acetate
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Buserelin
NSC_Code	725176
UMLS_CUI	C0006456
CAS_Registry	57982-77-1
Accepted_Therapeutic_Use_For	Breast cancer; Contraception, female; Endometriosis; Infertility; in vitro fertilization; Polycystic ovary syndrome; Prostate cancer; Uterine leiomyoma
In_Clinical_Trial_For	Prostate cancer
FDA_UNII_Code	PXW8U3YXDV
Contributing_Source	FDA
ALT_DEFINITION	An anticancer drug that belongs to the family of drugs called gonadotropin-releasing hormones. In prostate cancer therapy, buserelin blocks the production of testosterone in the testicles.NCI-GLOSS
PDQ_Open_Trial_Search_ID	39170
PDQ_Closed_Trial_Search_ID	39170
Chemical_Formula	C60H86N16O13
Legacy_Concept_Name	Buserelin
FULL_SYN	6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing Hormone-releasing Factor (Pig)PTDCP01294 BSRLABNCI 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig)SNNCI BUSERELINPTFDAPXW8U3YXDV HOE 766CNNCI S74-6766CNNCI EtilamideBRNCI ICI 123215CNNCI BuserelinPTNCI buserelinPTNCI-GLOSSCDR0000045180 BuserelineSYNCI
DEFINITION	A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH. (NCI04)NCI
code	C320
sameAs	Buserelin
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0003073
is someValuesFrom of	nodeID://b650380 nodeID://b651866 nodeID://b651867 nodeID://b651870 nodeID://b651871
is Has_Free_Acid_Or_Base_Form of	Buserelin Acetate
is sameAs of	Buserelin

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