About: Bleomycin Sulfate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bleomycin Sulfate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Antibiotic
Preferred_Name
  • Bleomycin Sulfate
UMLS_CUI
  • C0701921
CAS_Registry
  • 9041-93-4
Accepted_Therapeutic_Use_For
  • Squamous cell carcinomas of the head and neck; penis; cervix and vulva; Hodgkins and; non-Hodgkins lymphoma; testicular embryonal cell and ovarian carcinoma; chorio- and teratocarcinoma; malignant pleural effusion; melanoma; sarcoma; ovary germ cell tumor
FDA_UNII_Code
  • 7DP3NTV15T
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It comes from the bacterium Streptomyces verticillus. Blenoxane that damages DNA and may kill cancer cells. It is a type of antineoplastic antibiotic.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39139
PDQ_Closed_Trial_Search_ID
  • 39139
Legacy_Concept_Name
  • Bleomycin_Sulphate
CHEBI_ID
  • CHEBI:34582
FULL_SYN
  • BleMomycineBRNCI
  • bleomycin sulfatePTNCI-GLOSSCDR0000637625
  • Bleomycin SulfatePTDCP00636
  • BleocinSYDTPNSC0125066
  • Bleomycin SulfasSYNCI
  • Bleomycin SulfatePTNCI
  • Bleomycini SulfasSYNCI
  • BLEOMYCIN SULFATEPTFDA7DP3NTV15T
  • Bleo-SFBNCI
  • Bleomycin SulphateSYNCI
  • BleocinFBNCI
  • BleolemFBNCI
  • BlexaneSYNCI
  • BlenoxaneSYDTPNSC0125066
  • Oil BleoFBNCI
  • BlanoxanFBNCI
  • Bleomycin sulfateSYDTPNSC0125066
  • Bleo-cellFBNCI
  • BlenoxaneBRNCI
  • BlenoxanePTNCI-GLOSSCDR0000637626
DEFINITION
  • A mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.NCI
code
  • C312
sameAs
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Salt_Form of
is sameAs of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 40 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software