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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dyclonine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Dyclonine
NSC_Code
  • 23018
UMLS_CUI
  • C0058831
CAS_Registry
  • 586-60-7
FDA_UNII_Code
  • 078A24Q30O
Contributing_Source
  • FDA
Chemical_Formula
  • C18H27NO2
Legacy_Concept_Name
  • Dyclonine
CHEBI_ID
  • CHEBI:4724
FULL_SYN
  • DYCLONINEPTFDA078A24Q30O
  • 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-SNNCI
  • DycloninePTNCI
DEFINITION
  • An unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.NCI
code
  • C29015
sameAs
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