About: Divalproex Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Divalproex Sodium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Divalproex Sodium
UMLS_CUI
  • C0886883
CAS_Registry
  • 76584-70-8
FDA_UNII_Code
  • 644VL95AO6
Contributing_Source
  • FDA
Chemical_Formula
  • 2C8H15O2."H".Na
Legacy_Concept_Name
  • Divalproex
CHEBI_ID
  • CHEBI:4667
FULL_SYN
  • Depakote ERBRNCI
  • Abbott 50711CNNCI
  • Sodium DivalproexSYNCI
  • Divalproex SodiumPTNCI
  • DIVALPROEX SODIUMPTFDA644VL95AO6
  • EpivalBRNCI
  • EpilexBRNCI
  • Sodium Hydrogen Bis(2-propylpentanoate)SNNCI
  • DepakoteBRNCI
  • ValparinBRNCI
  • Valproate SemisodiumSYNCI
DEFINITION
  • A stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex dissociates to the valproate ion in the gastrointestinal tract. This agent binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. Divalproex may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.NCI
code
  • C28996
sameAs
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