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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefazolin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cefazolin
UMLS_CUI
  • C0007546
CAS_Registry
  • 25953-19-9
FDA_UNII_Code
  • IHS69L0Y4T
Contributing_Source
  • FDA
Chemical_Formula
  • C14H14N8O4S3
Legacy_Concept_Name
  • Cefazolin
CHEBI_ID
  • CHEBI:474053
FULL_SYN
  • CEFAZOLINPTFDAIHS69L0Y4T
  • (6R,7R)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic AcidSNNCI
  • CefazolinPTNCI
DEFINITION
  • A beta-lactam antibiotic and first-generation cephalosporin with bactericidal activity. Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C28913
sameAs
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