About: Calcipotriene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Calcipotriene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Calcipotriene
UMLS_CUI
  • C0065767
CAS_Registry
  • 112828-00-9
  • 112965-21-6
FDA_UNII_Code
  • 143NQ3779B
Contributing_Source
  • FDA
Chemical_Formula
  • C27H40O3
Legacy_Concept_Name
  • Calcipotriene
CHEBI_ID
  • CHEBI:50749
FULL_SYN
  • CALCIPOTRIENEPTFDA143NQ3779B
  • CalcipotriolSYNCI
  • CalcipotrienePTNCI
  • DovonexBRNCI
DEFINITION
  • A synthetic vitamin D derivative usually formulated for topical dermatological use, antipsoriatic Calcipotriene (calcipotriol) competes equally with active 1,25-hydroxy-2D3 (the natural form of vitamin D) for 1,25-hydroxy-2D3 receptors in regulating cell proliferation and differentiation. It induces differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and leads to normalization of epidermal growth. (NCI04)NCI
code
  • C28900
sameAs
http://linked.open...y/mesh/hasConcept
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