About: ALVAC-B7-CEA     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • ALVAC-B7-CEA
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • ALVAC-B7-CEA
NSC_Code
  • 674332
UMLS_CUI
  • C1515848
Legacy_Concept_Name
  • ALVAC-B7-CEA
FULL_SYN
  • ALVAC-B7-CEAPTNCI
DEFINITION
  • A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cells, and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28, to augment the host immune response. This agent has been shown to stimulate a host immune response against tumor cells that express CEA. (NCI04)NCI
code
  • C2742
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