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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Imidazole Mustard
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Imidazole Mustard
NSC_Code
  • 82196
UMLS_CUI
  • C0063382
CAS_Registry
  • 5034-77-5
In_Clinical_Trial_For
  • Refractory Primary Brain Tumor
PDQ_Open_Trial_Search_ID
  • 39483
PDQ_Closed_Trial_Search_ID
  • 39483
Legacy_Concept_Name
  • Imidazole_Mustard
FULL_SYN
  • TIC MustardSYNCI
  • 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamideSYDTPNSC0082196
  • BICABNCI
  • 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]-imidazole-4-carboxamideSYDTPNSC0082196
  • Imidazole MustardPTNCI
  • 5-[3,3-Bis(2-Chloroethyl)-1-Triazeno]Imidazole-4-CarboxamideSNNCI
  • Imidazole mustardSYDTPNSC0082196
  • TIC mustardSYDTPNSC0082196
DEFINITION
  • A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. (NCI04)NCI
code
  • C2216
http://linked.open...y/mesh/hasConcept
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