About: Class II AP Endonuclease     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Class II AP Endonuclease
rdfs:subClassOf
Semantic_Type
  • Enzyme
Preferred_Name
  • Class II AP Endonuclease
UMLS_CUI
  • C1333055
Legacy_Concept_Name
  • Class-II_AP-Endonuclease
FULL_SYN
  • Class II AP EndonucleasePTNCI
DEFINITION
  • Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. (From LocusLink 27301)NCI
code
  • C21422
is rdf:first of
is someValuesFrom of
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