About: Mediator Complex

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Mediator Complex
rdfs:subClassOf	Protein or Riboprotein Complex nodeID://b692227 nodeID://b692228 nodeID://b692229 nodeID://b692230
Semantic_Type	Amino Acid, Peptide, or Protein
Preferred_Name	Mediator Complex
UMLS_CUI	C1363844
Legacy_Concept_Name	Mediator_of_Activation
FULL_SYN	Mediator of ActivationSYNCI Mediator of RNA Polymerase II TranscriptionSYNCI Mediator ComplexPTNCI Mediator Coactivator ComplexSYNCI MediatorSYNCI Mediator CoactivatorSYNCI
DEFINITION	A protein complex that is involved in the initiation of transcription. This complex is composed of over 30 protein subunits, which binds to the RNA polymerase II holoenzyme complex and facilitates the interaction of transcription factors with the polymerase.NCI
DesignNote	The human Mediator complex is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11,MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26,MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. (UniProt)
code	C19864
is rdfs:subClassOf of	TRAP Complex Cofactor Required for SP1 Activation
is someValuesFrom of	nodeID://b658345 nodeID://b661937 nodeID://b689616 nodeID://b692235 nodeID://b702527 nodeID://b702547

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