About: Darbepoetin Alfa     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Darbepoetin Alfa
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Darbepoetin Alfa
NSC_Code
  • 729969
UMLS_CUI
  • C0937950
CAS_Registry
  • 209810-58-2
Accepted_Therapeutic_Use_For
  • Chemotherapy-induced anemia; chronic renal failure/insufficiency
In_Clinical_Trial_For
  • Chemotherapy-induced anemia
FDA_UNII_Code
  • 15UQ94PT4P
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance made in the laboratory that stimulates the bone marrow to produce red blood cells. It belongs to the family of drugs called antianemics.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38676
PDQ_Closed_Trial_Search_ID
  • 38676
Legacy_Concept_Name
  • Darbepoetin_Alfa
FULL_SYN
  • NESPABNCI
  • DARBEPOETIN ALFAPTFDA15UQ94PT4P
  • Darbepoetin AlfaPTNCI
  • NespoFBNCI
  • AranespBRNCI
  • Novel Erythropoiesis Stimulating ProteinSYNCI
  • darbepoetin alfaPTNCI-GLOSSCDR0000256550
DEFINITION
  • A recombinant analog of the endogenous cytokine erythropoietin, an erythropoiesis-stimulating protein. Due to the addition of two carbohydrate chains, darbepoetin alfa exhibits a three-fold greater half-life than does erythropoietin. Similar to erythropoietin, darbopoietin alfa binds to and activates epoetin receptors, thereby inducing the differentiation and maturation of erythrocyte progenitors, stimulating endothelial cell proliferation, and stimulating B-cell proliferation and immunoglobulin production. (NCI04)NCI
code
  • C1878
sameAs
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