About: Fc-Gamma Receptor II     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Fc-Gamma Receptor II
rdfs:subClassOf
Semantic_Type
  • Receptor
  • Immunologic Factor
Preferred_Name
  • Fc-Gamma Receptor II
UMLS_CUI
  • C0796385
Legacy_Concept_Name
  • Fc-Gamma_Receptor-II
FULL_SYN
  • Fc-Gamma Receptor IIPTNCI
DEFINITION
  • Generally expressed in monocytes, macrophages, polymorphonuclear cells, NK cells, T- and B-lymphocytes, and platelets, Fc-Gamma Receptors II are type I cell surface membrane protein low affinity receptors for aggregated IgG Fc region with 2 extracellular IgC2 domains and cytoplasmic ITIM or ITAM motifs involved in cell activation upon receptor aggregation. IgG binding initiates essential effector and regulatory cellular responses against foreign pathogens and soluble antigens that induce phagocytosis of antigen-antibody complexes, removing them from circulation, and modulate B-cell antibody production. (NCI)NCI
code
  • C18308
is rdf:first of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 13 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software