About: Beta Adrenergic Receptor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Beta Adrenergic Receptor
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Beta Adrenergic Receptor
UMLS_CUI
  • C0034785
Legacy_Concept_Name
  • Beta_Adrenergic_Receptor
FULL_SYN
  • Beta Adrenergic ReceptorPTNCI
DEFINITION
  • Expressed by Beta Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)NCI
code
  • C17062
sameAs
http://linked.open...y/mesh/hasConcept
is rdf:first of
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