About: ELISA

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	ELISA
rdfs:subClassOf	Enzyme Immunoassay
Concept_In_Subset	Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology CDISC SDTM Method Terminology
Semantic_Type	Laboratory Procedure
Preferred_Name	ELISA
UMLS_CUI	C0014441
Contributing_Source	CDISC
ALT_DEFINITION	An immunoassay for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way.CDISC An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.MSH2001 A laboratory technique that uses antibodies linked to enzymes to detect and measure the amount of a substance in a solution, such as serum. The test is done using a solid surface to which the antibodies and other molecules stick. In the final step, an enzyme reaction takes place that causes a color change that can be read using a special machine. There are many different ways that an ELISA can be done. ELISAs may be used to help diagnose certain diseases.NCI-GLOSS
Legacy_Concept_Name	ELISA
FULL_SYN	Enzyme-linked Immunosorbent AssaySYNCI ELISAPTNCI-GLOSSCDR0000655045 Enzyme-linked Immunosorbent AssaySYCDISC enzyme-linked immunosorbent assayPTNCI-GLOSSCDR0000655046 ELISAPTNCI ELISAPTCDISC
DEFINITION	A highly sensitive technique for detecting and measuring antigens or antibodies in a solution; the solution is run over a surface to which immobilized antibodies specific to the substance have been attached, and if the substance is present, it will bind to the antibody layer, and its presence is verified and visualized with an application of antibodies that have been tagged in some way. (BioTech Life Science Dictionary)NCI
code	C16553
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0007526

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