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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Levoleucovorin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Levoleucovorin
UMLS_CUI
  • C2721771
CAS_Registry
  • 58-05-9
FDA_UNII_Code
  • 990S25980Y
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 40490
PDQ_Closed_Trial_Search_ID
  • 40490
Chemical_Formula
  • C20H23N7O7
Legacy_Concept_Name
  • L-Leucovorin
CHEBI_ID
  • CHEBI:63606
FULL_SYN
  • L-LeucovorinSYNCI
  • LevofolinateSYNCI
  • LEVOLEUCOVORINPTFDA990S25980Y
  • LevoleucovorinPTNCI
  • L-5-FormyltetrahydrofolateSNNCI
  • Levofolinic acidSYNCI
  • Elvorine, Isovorin, Levofolene, LevorinFBNCI
  • IsovorinBRNCI
  • CL-307,782CNNCI
DEFINITION
  • The active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known levoleucovorin, does not require bioactivation by dihydrofolate reductase, an enzyme inhibited by folic acid antagonists. This agent may enhance the effects of fluoropyrimidines by stabilizing their binding to the enzyme thymidylate synthase. (NCI04)NCI
code
  • C1559
sameAs
is someValuesFrom of
is Has_Free_Acid_Or_Base_Form of
is sameAs of
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