About: Clodronate Disodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Clodronate Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Organophosphorus Compound
Preferred_Name
  • Clodronate Disodium
NSC_Code
  • 713466
UMLS_CUI
  • C0008994
CAS_Registry
  • 88416-50-6
Accepted_Therapeutic_Use_For
  • Adjuvant usage in bone metastasis of Breast cancer
FDA_UNII_Code
  • N030400H8J
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used as treatment for hypercalcemia (abnormally high levels of calcium in the blood) and for cancer that has spread to the bone (bone metastases). It may decrease pain, the risk of fractures, and the development of new bone metastases.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41862
PDQ_Closed_Trial_Search_ID
  • 41862
Chemical_Formula
  • CH2Cl2O6P2.2Na.4H2O
Legacy_Concept_Name
  • Clodronate_Disodium
CHEBI_ID
  • CHEBI:59587
FULL_SYN
  • clodronatePTNCI-GLOSSCDR0000045405
  • BonefosSYDTPNSC0713466
  • LoronFBNCI
  • Clodronic Acid Disodium SaltSYNCI
  • CL2MDPCNNCI
  • MebonatFBNCI
  • BonefosFBNCI
  • OssitenFBNCI
  • Clodronate DisodiumPTNCI
  • ClasteonFBNCI
  • CLODRONATE DISODIUMPTFDAN030400H8J
  • Dichloromethylene DiphosphonateSYNCI
  • DifosfonalFBNCI
  • ClodronateSYNCI
DEFINITION
  • The disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain.NCI
code
  • C1418
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Salt_Form of
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