About: Lung Surfactant

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Lung Surfactant
rdfs:subClassOf	Respiratory System Fluid or Secretion
Concept_In_Subset	Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology CDISC SDTM Specimen Type Terminology
Semantic_Type	Body Substance
Preferred_Name	Lung Surfactant
UMLS_CUI	C0034085
Contributing_Source	CDISC
ALT_DEFINITION	Pulmonary surfactant lines the lung epithelium and lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis. (NCI)CDISC phospholipids secreted by the great alveolar cells into alveoli and respiratory air passages which contributes to the elastic property of pulmonary tissue.CSP2000 Lipoproteins in which the lipid moiety is based mainly on lecithin and other phospholipids. They may also contain small amounts of prostaglandins and other compounds. They are secreted by the mitochondria of type II alveolar cells. Surfactants regulate the surface tension of the mucoid layer lining the alveoli.MSH2001
Legacy_Concept_Name	Lung_Surfactant
FULL_SYN	SurfactantSYCDISC Lung SurfactantPTNCI Surfactant, LungSYNCI LUNG SURFACTANTPTCDISC SurfactantSYNCI
DEFINITION	Pulmonary surfactant lines the lung epithelium and lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis.NCI
code	C13273
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0018140

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