About: Toremifene

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Toremifene
rdfs:subClassOf	Selective Estrogen Receptor Modulator
Has_Salt_Form	TOREMIFENE CITRATE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Toremifene
UMLS_CUI	C0076836
CAS_Registry	89778-26-7
Accepted_Therapeutic_Use_For	Breast cancer; Desmoid tumors
In_Clinical_Trial_For	Advanced breast cancer; prostate cancer
FDA_UNII_Code	7NFE54O27T
Contributing_Source	FDA
ALT_DEFINITION	An anticancer drug that belongs to the family of drugs called antiestrogens. Toremifene blocks the effect of the hormone estrogen in the body. It may help control some cancers from growing, and it may delay or reduce the risk of cancer recurrence.NCI-GLOSS
PDQ_Open_Trial_Search_ID	41103
PDQ_Closed_Trial_Search_ID	41103
Chemical_Formula	C26H28ClNO
Legacy_Concept_Name	Toremifene
CHEBI_ID	CHEBI:9635
FULL_SYN	toremifenePTNCI-GLOSSCDR0000045338 ToremifenePTDCP08997 (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamineSNNCI (Z)-4-Chloro-1,2-diphenyl-1[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-1-buteneSNNCI TOREMIFENEPTFDA7NFE54O27T ToremifenePTNCI
DEFINITION	A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04)NCI
code	C1256
sameAs	TOREMIFENE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0026287
is someValuesFrom of	nodeID://b647468 nodeID://b660558 nodeID://b663208 nodeID://b663253 nodeID://b674212 nodeID://b683215
is Has_Free_Acid_Or_Base_Form of	TOREMIFENE CITRATE
is sameAs of	TOREMIFENE TOREMIFENE

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